Drug intelligence / Profile preview

caulophyllum thalictroides

Development stage
Unknown
Lead developer
Boiron
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Sublingual
01

Overview

Caulophyllum thalictroides is a homeopathic preparation derived from the roots of the blue cohosh plant. Developed and manufactured by Boiron, it is primarily used in the fields of gynecology and obstetrics. In clinical practice, it is often administered as sublingual pellets at various potencies, such as 9CH. It has been investigated in Phase 3 clinical trials, often in combination with Actaea racemosa, to evaluate its efficacy in shortening the duration of the first stage of labor. Beyond obstetrics, it is traditionally used for menstrual cramps, premenstrual syndrome (PMS), and rheumatic pain in small joints. As a homeopathic product, its mechanism of action does not involve conventional pharmacological targets, and its clinical efficacy remains a subject of debate due to the high level of dilution.

Brand names
Caulophyllum thalictroides 9CH
Other names
blue cohoshblue ginsengsquaw rootpapoose root

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