cavia porcellus dander

Cavia porcellus dander is a non-standardized allergenic extract derived from the dander of the domesticated guinea pig (*Cavia porcellus*). It is primarily utilized as a diagnostic tool in allergy testing to identify Type I hypersensitivity (allergic sensitization) in patients, particularly those with occupational exposure such as laboratory animal workers, veterinarians, or pet owners. The extract contains a complex mixture of proteins that act as allergens; when administered via skin prick (topical) or intradermal (subcutaneous) injection, these proteins cross-link allergen-specific IgE antibodies bound to the surface of mast cells and basophils. This interaction triggers the release of inflammatory mediators like histamine, resulting in a visible wheal-and-flare reaction at the test site. While its primary use is diagnostic, such extracts are also used in allergen immunotherapy (hyposensitization) to reduce clinical symptoms upon subsequent exposure.

Other names

guinea pig dander extractguinea pig allergenic extract