Drug intelligence / Profile preview

CBD Daye Tampon

Development stage
Preclinical
Lead developer
Daye
Modality
Small Molecules
Administration
Vaginal
01

Overview

**CBD Daye Tampon** is a Daye menstrual tampon product consisting of an organic cotton tampon coated with a proprietary, THC-free hemp-derived cannabinoid extract in which cannabidiol is the principal stated active constituent. The product is inserted vaginally for menstrual care and has been studied for symptomatic relief of primary dysmenorrhea, including menstrual cramps and pain. Daye describes a proposed local mechanism involving endocannabinoid signaling in vaginal and uterine tissues; however, definitive target engagement and clinical efficacy for therapeutic use remain insufficiently established. A randomized, single-blinded, placebo-controlled study involving 63 participants was published for cannabidiol-infused tampons in primary dysmenorrhea. FDA cleared the underlying Daye Tampon for menstrual-fluid absorption under 510(k) K223883, but FDA subsequently warned that the CBD-coated product and its therapeutic claims constituted an uncleared major modification and lacked the required marketing authorization for that intended use. ([sciencedirect.com](https://www.sciencedirect.com/science/article/pii/S2949838423000452))

Brand names
CBD Daye Tampon
Other names
CBD Daye TamponsCBD TamponDaye CBD Tampon
02

Targets

CNR1 (Cannabinoid receptor 1)

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