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CBP-233 is a monoclonal antibody that targets interleukin-33 (IL-33), acting as an IL-33 inhibitor. It was developed by Suzhou Connect Biopharma (Connect Biopharmaceuticals) for the treatment of various serious inflammatory conditions, particularly those involving type 2 inflammation such as allergic and other chronic inflammatory diseases. The drug is currently in preclinical development, with its primary mechanism being the inhibition of IL-33 signaling, which plays a key role in mediating immune responses associated with inflammation[1][2][3][5].
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