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CBP-246 is a monoclonal antibody that targets the interleukin-1 receptor accessory protein (IL-1RAcP), acting as an inhibitor of this protein. It was developed by Suzhou Connect Biopharma and is designed to modulate type 2 inflammatory diseases by blocking IL1RAP-mediated signaling pathways. The drug was in preclinical development for inflammation and other type 2 inflammatory conditions but has since been discontinued[1][4][10].
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