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Drug intelligence / Profile preview
CBT-005
- Development stage
- Preclinical
- Lead developer
- Cloudbreak Pharma
- Modality
- Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Ophthalmic, Subcutaneous
01
Overview
CBT-005 is an ophthalmic drug candidate attributed to Cloudbreak Therapeutics. Drug databases describe it as an antibody-drug conjugate associated with VEGF-A inhibition and VEGF receptor antagonism and report preclinical development for wet age-related macular degeneration and diabetic macular edema. These details have not been independently confirmed in a qualifying primary source. ([synapse.patsnap.com](https://synapse.patsnap.com/drug/8608212291564d5b8aae70d2f9c3d2ac))
02
Targets
FGFR (Fibroblast growth factor receptor)NPR2 (C-type Natriuretic Peptide Receptor B)PDGFR (PDGFR family)VEGFA (Vascular endothelial growth factor A)VEGFR-1 (Vascular endothelial growth factor receptor 1)VEGFR2 (Vascular endothelial growth factor receptor 2)VEGFR4 (Vascular endothelial growth factor Receptor-3)
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