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CBT-104A
- Development stage
- Unknown
- Lead developer
- CommBio Therapeutics
- Modality
- Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, CRISPR-Cas9 → CRISPR Systems → Programmable Nucleases → Gene Editing → Gene Therapies, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
CBT-104A is an engineered bacterial therapeutic being developed by CommBio Therapeutics for the treatment of Inflammatory Bowel Disease (IBD). It is a product of CommBio's proprietary bacterial vector gene therapy platform, which utilizes CRISPR-Cas9 and other gene-editing technologies to modify bacteria for therapeutic use. The drug is designed to address intestinal dysfunction and inflammatory conditions by leveraging the modified bacteria to act within the gut environment. CBT-104A is part of the CBT-104 series and represents a novel modality in treating complex immune-mediated diseases through microbial engineering.
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