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CBT-104B

Development stage: Unknown
Lead developer: CommBio Therapeutics
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics

Overview

CBT-104B is an engineered bacterial therapeutic being developed by CommBio Therapeutics for the treatment of Systemic Lupus Erythematosus (SLE). As part of CommBio's pipeline of live biotherapeutic products (LBPs), CBT-104B utilizes synthetic biology to engineer bacteria that can modulate the host's immune system or metabolic environment to address the underlying pathology of lupus. The drug is currently in the early stages of clinical development, categorized as being in clinical research or Phase 1.

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