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CBT-202

Development stage: Preclinical
Lead developer: CommBio Therapeutics
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral

Overview

CBT-202 is an engineered bacterial live biotherapeutic product (LBP) being developed by CommBio Therapeutics for smoking cessation. The drug candidate consists of genetically modified bacteria designed to target nicotine or its metabolic pathways, aiming to reduce nicotine levels in the body or mitigate the addictive effects of smoking. Currently, the program is in the early preclinical stage of development, focused on strain construction and optimization.

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