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CC-02-4

Development stage: Preclinical
Lead developer: CompleCure
Modality: Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration: Intravenous

Overview

**CC-02-4** is a preclinical, HER2-targeted antibody-drug conjugate being developed by CompleCure for HER2-positive unresectable advanced or recurrent colorectal cancer. CompleCure identifies CC-02-4 as part of its CC-02 ADC series, for which doxorubicin payload use is reported, and notes development in combination with the separate anti-HER2 antibodies trastuzumab and pertuzumab. The specific antibody, linker chemistry, exact payload configuration, route, and dosage form have not been publicly disclosed. ([complecure.com](https://www.complecure.com/en))

Targets

TUBB (Tubulin (alpha and beta subunits))DNAERBB2 (Erb-b2 receptor tyrosine kinase 2)

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