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CC2202 is an investigational circular RNA (circRNA) therapeutic candidate developed by CirCode Bio (环码生物) for the treatment of oncology indications. Utilizing CirCode's proprietary circular RNA platform, CC2202 is designed to overcome the stability limitations of traditional linear mRNA. Circular RNAs are covalently closed loops that lack 5' and 3' ends, making them resistant to exonuclease-mediated degradation and potentially allowing for more sustained and robust protein expression within target cells. CC2202 is typically formulated with lipid nanoparticles (LNPs) for delivery and is intended to express therapeutic proteins that modulate the tumor microenvironment or directly inhibit tumor growth. It is currently in the preclinical stage of development.
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