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CCT-817 is a preclinical-stage small interfering RNA (siRNA) therapeutic being developed by Canary Cure (also known as Canary Global) for the treatment of obesity and metabolic dysfunction-associated steatohepatitis (MASH). Developed using the company's 'Reprogram Platform' and 'Thermogenic Adipose Reprogramming' technology, CCT-817 is designed to promote the 'browning' of white adipose tissue (WAT). This process involves reprogramming energy-storing white adipocytes into energy-expending thermogenic adipocytes, thereby increasing metabolic rate and facilitating weight loss. The drug is part of a pipeline focused on thermogenic adipose reprogramming to address metabolic diseases through targeted gene silencing.
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