Drug intelligence / Profile preview

CCT128930

Development stage
Preclinical
Lead developer
The Institute of Cancer Research
Modality
Small Molecules
Administration
Oral
01

Overview

CCT128930 is a small molecule inhibitor developed as a selective and orally bioavailable inhibitor of Protein kinase B (PKB/Akt). It was designed to target the PKB/Akt pathway with high selectivity and has demonstrated in vivo antitumor activity in preclinical models. The compound is experimental and has not been approved for any indication. Its primary mechanism of action is inhibition of PKB/Akt signaling—a key pathway involved in cell survival and proliferation—making it a potential candidate for cancer therapy[3][6][1].

Other names
1-[4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-yl]methanamine4-(4-chlorobenzyl)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-amine4-[ (4-chlorophenyl)methyl ] -1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)piperidin-4-methanamine
02

Targets

CHEK2 (Checkpoint kinase 2)ROCK2 (Rho-associated coiled-coil containing protein kinase 2)AKT2 (Rac-beta serine/threonine-protein kinase)RPS6KB1 (Ribosomal protein S6 kinase beta-1)PKA (Cyclic amp-dependent protein kinase)

Beyond the preview

Go deeper on CCT128930.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on CCT128930.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call