Drug intelligence / Profile preview

CD33-CAR-T cell infusion

Development stage
Unknown
Lead developer
Precigen
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

CD33-CAR-T cell infusion is a type of Chimeric Antigen Receptor T-cell (CAR-T cell) therapy developed by Precigen. It is designed to treat acute myeloid leukemia (AML) by targeting the CD33 antigen on cancer cells. The therapy involves engineering a patient's T-cells to express a chimeric antigen receptor that specifically recognizes and binds to CD33, leading to the destruction of CD33-expressing leukemia cells.

Other names
Anti-CD33 CAR T CellsAnti-CD-33 CAR T CellsAnti-CD 33 CAR T CellsAnti-CD33 CAR-T CellsAnti-CD-33 CAR-T CellsAnti-CD 33 CAR-T CellsCD33-CAR T CellsCD-33-CAR T CellsCD 33-CAR T CellsCART-33CART33CART 33
02

Targets

SIGLEC6 (Siglec-6)CD33 (Myeloid cell surface antigen CD33)

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