Drug intelligence / Profile preview

CD7 CAR-T cells injection

Development stage
Unknown
Lead developer
Zhejiang University
Modality
CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

**CD7 CAR-T cells injection** is an investigational CD7-directed chimeric antigen receptor T-cell therapy being studied by Zhejiang University as part of a sequential treatment strategy followed by allogeneic hematopoietic stem-cell transplantation. In the registered early-phase study for non-malignant blood and immune-system diseases, the product is intended for patients with hereditary bone-marrow-failure syndromes, congenital immunodeficiency, and transfusion-dependent hemoglobinopathies who have an indication for allogeneic transplantation. The CAR-T cells recognize CD7-expressing T cells, producing CD7-positive T-cell depletion before transplantation; allo-HSCT is a separate procedural component of the clinical strategy rather than an ingredient of the cell product.

Other names
CD7 CAR-T cellsCD-7 CAR-T cellsCD 7 CAR-T cellsCD7-targeted CAR-T cellsCD-7-targeted CAR-T cellsCD 7-targeted CAR-T cells
02

Targets

CD7 (CD7 antigen)

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