Drug intelligence / Profile preview

CDD-1653

Development stage
Unknown
Lead developer
Baylor College of Medicine
01

Overview

CDD-1653: sourced facts only. name: "Structure-activity relationship studies addressed metabolic lability and high-molecular-weight issues, resulting in potent and BMPR2-selective inhibitor analogs CDD-1281 (IC50 = 1.2 nM) and CDD-1653 (IC50 = 2.8 nM), respectively." [PMID:36719862]; target: "Structure-activity relationship studies addressed metabolic lability and high-molecular-weight issues, resulting in potent and BMPR2-selective inhibitor analogs CDD-1281 (IC50 = 1.2 nM) and CDD-1653 (IC50 = 2.8 nM), respectively." [PMID:36719862]; developer: "Center for Drug Discovery, Department of Pathology & Immunology, Baylor College of Medicine, Houston, Texas77030, United States." [PMID:36719862]

02

Targets

BMPR2 (Bone morphogenetic protein receptor type II)

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