Drug intelligence / Profile preview

CDR701

Development stage
Preclinical
Lead developer
CDR-Life
Modality
T-cell Engagers → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Antibody Fragments → Engineered Antibody Formats → Antibody-Based Therapeutics
Administration
Intravenous, Subcutaneous
01

Overview

CDR701 is an investigational, antibody-fragment-based T-cell engager (TCE) developed by CDR-Life using its proprietary M-gager® platform. It is designed to target an undisclosed cleaved tumor-associated antigen on solid tumors. By binding to both the cleaved tumor antigen on cancer cells and the CD3 receptor on T cells, CDR701 recruits and activates T cells to selectively eliminate tumor cells while sparing healthy tissues. The program is currently in the discovery/preclinical stage of development for the treatment of solid tumors.

02

Targets

CD3 (T-cell surface glycoprotein CD3)Kita-Kyushu lung cancer antigen 1 peptide-human leukocyte antigen class I complex

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