Drug intelligence / Profile preview

CDX-301

Development stage
Preclinical
Lead developer
Celldex Therapeutics
Modality
Small Molecules
Administration
Subcutaneous, Intratumoral, Intracutaneous
01

Overview

CDX-301 is a small molecule pharmaceutical candidate developed by Cardax, utilizing zeaxanthin as its active ingredient. Zeaxanthin is a xanthophyll carotenoid that naturally and selectively accumulates in the human macula through uptake by a unique retinal receptor. The drug is being developed for the treatment of macular degeneration, with Stargardt disease as the target initial indication. CDX-301 functions through general antioxidant and anti-inflammatory mechanisms, specifically protecting the retina from oxidative stress, blue light-induced damage, and associated inflammation. As of the current development status, CDX-301 is in the pre-clinical phase, with plans for IND-enabling studies and potential monetization through licensing or sale.

Other names
zeaxanthin pharmaceutical candidatezeaxanthin-based pharmaceutical
02

Targets

FLT3 (Fms related receptor tyrosine kinase 3)

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