Drug intelligence / Profile preview

cecropin B

Development stage: Unknown
Modality: Peptides
Administration: Intraperitoneal, Intravenous

Overview

Cecropin B is a 35-amino acid cationic antimicrobial peptide derived from the giant silk moth, *Hylphora cecropia*. It functions as an antibacterial and anti-cancer agent by disrupting bacterial and cancerous cell membranes. Cecropin B has a helix-hinge-helix structure, which allows it to interact with microbial membranes, leading to cell death. It exhibits low cytotoxicity against mammalian cells, making it a potential therapeutic agent.

Targets

CM (Bacterial cytoplasmic membrane (Gram-negative))

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