Drug intelligence / Profile preview

cefditoren

Development stage
Approved
Lead developer
Meiji Seika Pharma
Modality
Small Molecules
Administration
Oral
01

Overview

Cefditoren is a third-generation cephalosporin antibiotic used to treat infections caused by Gram-positive and Gram-negative bacteria, including those resistant to other antibiotics. It is primarily indicated for community-acquired pneumonia, acute bacterial exacerbation of chronic bronchitis, pharyngitis, tonsillitis, uncomplicated skin and skin structure infections, and otitis media. Cefditoren is administered orally as the prodrug cefditoren pivoxil, which is hydrolyzed in the body to its active form. Its mechanism of action involves inhibiting bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to bactericidal activity. Cefditoren demonstrates stability against many common beta-lactamases[4][5][6][7].

Brand names
Spectracef
Other names
cefditoren pivoxil
02

Targets

PBP1A (Penicillin-binding protein 1A)PBP2B (Penicillin-binding protein 2B)

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