ceforanide

Ceforanide is a semisynthetic, second-generation cephalosporin antibiotic belonging to the β-lactam class. It is administered parenterally and has a relatively long elimination half-life compared to other cephalosporins. Ceforanide exhibits bactericidal activity by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. Its antibacterial spectrum includes many gram-negative organisms such as Escherichia coli, Klebsiella, Enterobacter, Proteus, Salmonella, Shigella, Hemophilus influenzae (including beta-lactamase-producing strains), Citrobacter, and Arizona species; it also covers some gram-positive bacteria but is less active against them than certain other cephalosporins. Clinically, ceforanide has been used for bone and joint infections, endocarditis, respiratory tract infections, skin infections, surgical infection prophylaxis or treatment, urinary tract infections (UTIs), bacteremia/ sepsis[1][2][3][4][5][6].

Brand names

RADACEF