cefoxitin

Cefoxitin is a semi-synthetic, broad-spectrum antibiotic of the cephamycin class, often grouped with second-generation cephalosporins. It is administered intravenously and used to treat a wide range of serious bacterial infections, including those of the urinary tract, blood, bones and joints, lower respiratory tract (such as pneumonia), skin and soft tissue, abdomen (including peritonitis), female reproductive organs (such as pelvic inflammatory disease), and for prevention of infection during certain surgical procedures. Cefoxitin acts by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), leading to cell lysis and death. Its methoxy group at the 7α position confers stability against many beta-lactamases produced by Gram-negative bacteria. Cefoxitin was developed from cephamycin C produced by Streptomyces lactamdurans[2][5][6][8].

Brand names

Mefoxin

Other names

cephamycin C derivative