cefpiramide

Cefpiramide is a third-generation, semi-synthetic cephalosporin antibiotic with a broad spectrum of antibacterial activity, including efficacy against *Pseudomonas aeruginosa* and both gram-positive and gram-negative bacteria[1][3][5]. It acts by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), specifically targeting the final cross-linking stage of peptidoglycan production in the bacterial cell wall[1][2][4]. Cefpiramide is rapidly absorbed following intramuscular injection, has high protein binding (93%–99.3%), and an elimination half-life of approximately 4.44 hours[3]. It is primarily excreted renally and fecally. The drug was launched in 1989 for use in susceptible infections[5].

Brand names

anti-pseudomonal

Other names

cefpiramide sodium