Drug intelligence / Profile preview

cefteram pivoxil

Development stage
Unknown
Lead developer
Chugai Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Cefteram pivoxil is an orally active, third-generation cephalosporin antibiotic. It is a prodrug that is rapidly hydrolyzed to its active form, cefteram, following oral administration. The drug works by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs), which prevents the cross-linking of peptidoglycan layers essential for bacterial structural integrity. It exhibits a broad spectrum of activity against Gram-positive and Gram-negative pathogens, including *Streptococcus pneumoniae*, *Haemophilus influenzae*, and various members of the Enterobacteriaceae family. It is primarily indicated for respiratory, urinary, and skin infections.

Brand names
Tomiron
Other names
Cefteramum pivoxilum
02

Targets

PBP (Penicillin-binding protein family)

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