ceftriaxone + cloxacillin

This drug is a combination of two antibiotics, ceftriaxone and cloxacillin, used together to treat bacterial infections. Ceftriaxone is a third-generation cephalosporin antibiotic with broad-spectrum activity against gram-negative and some gram-positive bacteria. It works by inhibiting bacterial cell wall synthesis, leading to cell death. Cloxacillin is a beta-lactamase-resistant penicillin antibiotic effective primarily against penicillinase-producing staphylococci; it also inhibits bacterial cell wall synthesis. The combination leverages the broad coverage of ceftriaxone with the staphylococcal coverage of cloxacillin, making it useful for mixed infections or empirical therapy where both types of bacteria are suspected.

Other names

ceftriaxone + cloxapen