Drug intelligence / Profile preview

cefuroxime axetil + clavulanic acid

Development stage
Unknown
Lead developer
Pharma Drugs & Chemicals
Modality
Small Molecules
Administration
Oral
01

Overview

Cefscot is a combination antibiotic medication consisting of cefuroxime axetil and potassium clavulanate. Cefuroxime axetil is a second-generation cephalosporin that exerts its bactericidal effect by inhibiting bacterial cell wall synthesis through binding to penicillin-binding proteins (PBPs). Potassium clavulanate is a beta-lactamase inhibitor that prevents the degradation of cefuroxime by beta-lactamase-producing bacteria, thereby extending its spectrum of activity. This combination is typically used for the treatment of respiratory tract infections, urinary tract infections, and skin and soft tissue infections caused by susceptible organisms. It is marketed as a branded generic by Pharma Drugs & Chemicals, often under a PCD (Propaganda Cum Distribution) franchise model.

Brand names
Cefscot
Other names
Cefscot-500 CVCefscot500 CVCefscot 500 CV
02

Targets

PBP1a/1b (Penicillin-binding protein 1a and 1b (PBP1a and PBP1b))Class A BL (Class A beta-lactamase)PBP2x (Penicillin-binding protein 2x)PBP3 (Peptidoglycan D,D-transpeptidase FtsI)

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