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Cejinzhan
- Development stage
- Unknown
- Lead developer
- Shandong institutions
- Modality
- Small Molecules
- Administration
- Oral, Topical
01
Overview
Cejinzhan is a botanical drug developed by the Shandong Institute of Biological Medicine, specifically indicated for the treatment of recurrent aphthous ulcers (RAU). It is derived from the plant *Adonis amurensis*, which contains various bioactive compounds including cardiac glycosides and flavonoids. In the treatment of RAU, Cejinzhan is valued for its anti-inflammatory, analgesic, and tissue-regenerative properties. The drug's mechanism involves the modulation of the local and systemic immune response, characterized by the suppression of pro-inflammatory cytokines such as TNF-alpha, IL-2, IL-6, and IL-8, and the balancing of T-lymphocyte subsets. Available in formulations such as oral liquids and topical films, Cejinzhan helps to alleviate the intense pain of oral sores and significantly shortens the healing time of the lesions. It is a recognized therapeutic option in China for patients suffering from chronic or recurrent oral ulcerations.
- Brand names
- Cejinzhan
- Other names
- Adonis amurensis extractCejinzhan Oral LiquidCejinzhan FilmCejinzhanhua
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)IL-2 (Interleukin 2)IL8 (C-X-C Motif Chemokine Ligand 8)
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