Drug intelligence / Profile preview

CelAgace OraRinse

Development stage
Phase 2
Lead developer
CelaCare Technologies
Modality
Small Molecules
Administration
Topical
01

Overview

**CelAgace OraRinse** is an investigational topical oral-rinse combination developed by CelaCare for oral candidiasis associated with mild-to-moderate oral mucositis, including in immunosuppressed and chemotherapy-treated patients. The formulation contains a silver citrate complex and acemannan, a purified polysaccharide extract from the inner leaf gel of *Aloe vera*. Silver citrate complex is intended to provide broad topical antimicrobial activity against yeast organisms, while acemannan is included as an oral-care and tissue-supportive component. The product has been registered in a Phase 1/2 pilot clinical study for candidiasis associated with Grade 0-II mucositis.

Brand names
CelAgace OraRinse
Other names
silver citrate complex + acemannansilver citrate complex and acemannan
02

Targets

Microbial membrane thiol-rich proteins

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