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A combination of celecoxib, a COX-2 inhibitor NSAID, and buprenorphine, an opioid analgesic. This combination leverages complementary mechanisms of action for pain management. Clinical studies have shown that the combination of buprenorphine transdermal patch with celecoxib capsules provides superior pain relief and functional improvement compared to either medication used alone, particularly in conditions like adhesive shoulder capsulitis.
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