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celecoxib + cholecalciferol
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
A combination of celecoxib, a nonsteroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2), and cholecalciferol (vitamin D3). Celecoxib is used to treat pain and inflammation in conditions like osteoarthritis and rheumatoid arthritis. Cholecalciferol is used to treat vitamin D deficiency. Research suggests this combination may have synergistic effects in certain conditions, with studies showing enhanced anti-cancer effects in breast cancer cell lines and potential for vitamin D to ameliorate celecoxib-induced cardiotoxicity.
- Other names
- celecoxib + vitamin D3
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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