Drug intelligence / Profile preview

celecoxib oral solution

Development stage
Approved
Lead developer
Dr. Reddy's Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

Elyxyb is a ready-to-use oral solution formulation of celecoxib, a nonsteroidal anti-inflammatory drug (NSAID) and selective cyclooxygenase-2 (COX-2) inhibitor. It is indicated for the acute treatment of migraine with or without aura in adults. Elyxyb uses a self-microemulsifying drug delivery system to improve solubility and bioavailability, resulting in faster absorption compared to standard formulations. The mechanism of action involves inhibition of prostaglandin synthesis by selectively blocking COX-2, thereby reducing inflammation and pain signaling associated with migraine attacks. The most common adverse reaction is dysgeusia; serious risks include cardiovascular thrombotic events and gastrointestinal bleeding or ulceration[1][6][8].

Brand names
Elyxyb
Other names
celecoxib oral solutionELYXYB
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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