Drug intelligence / Profile preview

Celixir20

Development stage
Phase 3
Lead developer
BOL Pharma
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Sublingual
01

Overview

**Celixir20** is a BOL Pharma cannabinoid-based sublingual medicated oil containing a high-cannabidiol, low-delta-9-tetrahydrocannabinol cannabis preparation. BOL Pharma describes Celixir20 as approved by the Israeli Ministry of Health for autism, while its medicated-drops portfolio identifies the formulation as approximately 20% cannabidiol and 1% delta-9-tetrahydrocannabinol. It has also been used in severe drug-resistant epilepsy, including pediatric patients, and has been listed for epilepsy in young adults and palliative care for hepatoma. The product is a chemically heterogeneous cannabis extract preparation rather than a single defined molecular entity. ([bolpharma.com](https://www.bolpharma.com/innovation/))

Brand names
Celixir20Celixir-20Celixir 20Noidecs T1:C20
02

Targets

CNR1 (Cannabinoid receptor 1)CNR2 (Cannabinoid receptor type 2)GPR55 (G protein-coupled receptor 55)TRPV1 (Transient receptor potential cation channel subfamily V member 1)

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