Drug intelligence / Profile preview

Cell-free fat extract

Development stage
Phase 2
Lead developer
SEME Cell Technology
Modality
Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Intradermal, Subcutaneous, Topical, Intrathecal, Local Injection
01

Overview

Cell-free fat extract (CEFFE) is a novel therapeutic agent derived from liposuction waste. It is the liquid fraction isolated mechanically from fat tissue after removing cell components, lipid residues, oil droplets, cell fragments, and extracellular matrix. CEFFE contains various growth factors and cytokines similar to stem cell paracrine factors, including vascular endothelial growth factor (VEGF), insulin-like growth factor (IGF), hepatocyte growth factor (HGF), brain-derived neurotrophic factor (BDNF), transforming growth factor-β (TGF-β), basic fibroblast growth factor (b-FGF), platelet-derived growth factor (PDGF), epidermal growth factor (EGF), and neurotrophic factor (NT-3). These components promote tissue regeneration, neovascularization, and have anti-inflammatory effects.

Other names
ATE
02

Targets

AR (Adrenergic receptors)

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