Drug intelligence / Profile preview

CELLISTEM-OA

Development stage
Phase 2
Lead developer
Cells for Cells
Modality
Stem Cell Therapies → Cell Therapies
Administration
Intraarticular
01

Overview

CELLISTEM-OA is an autologous cell therapy product composed of adipose-derived mesenchymal stem cells (AD-MSCs), specifically developed for the treatment of osteoarthritis, particularly of the knee. Developed by the Turkish biotechnology company Cellistem, the treatment involves harvesting a patient's own adipose tissue, followed by the isolation, expansion, and characterization of mesenchymal stem cells in a GMP-certified facility. These cells are then administered via intra-articular injection into the affected joint. The therapeutic effect is mediated through the secretion of various bioactive molecules (paracrine effect) that modulate the inflammatory environment, inhibit pro-inflammatory cytokines, and promote the repair of damaged articular cartilage. It is intended for patients with degenerative joint disease who have not responded to conventional pharmacological or physical therapies.

Brand names
CELLISTEM-OA
Other names
Autologous adipose-derived mesenchymal stem cellsAD-MSCs

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