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Cellspan Esophageal Implant
- Development stage
- Unknown
- Lead developer
- Harvard Apparatus Regenerative Technology
- Modality
- Device-based Delivery → Drug Delivery Systems, Stem Cell Therapies → Cell Therapies
- Administration
- Surgical Implantation
01
Overview
The Cellspan Esophageal Implant (CEI) is a tissue-engineered combination product developed by Harvard Apparatus Regenerative Technology (now Biostage). It consists of a biocompatible, synthetic scaffold seeded with a patient's own adipose-derived mesenchymal stem cells (MSCs). The implant is designed to stimulate the regeneration of a functional, living biologic esophageal conduit in patients requiring full circumferential esophageal reconstruction, such as those with esophageal cancer or pediatric esophageal atresia. The product aims to replace segments up to 6 cm in length, providing a structural framework that facilitates tissue growth and integration.
- Brand names
- CellspanCellspan Esophageal Implant
- Other names
- Cellspan Esophageal Implant-Adult
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