centella asiatica water extract

Centella asiatica water extract is an aqueous preparation derived from the plant Centella asiatica, also known as gotu kola or cica. It contains bioactive triterpene glycosides such as asiaticoside and madecassoside and their aglycones asiatic acid and madecassic acid. The primary mechanisms of action are believed to involve antioxidant activity, anti-inflammatory effects, enhancement of skin barrier function, and neuroprotective properties. Preclinical studies suggest benefits for cognitive health (including potential prevention or treatment of cognitive decline), wound healing, skin hydration, and reduction of oxidative stress[1][5][6]. The product is widely used in cosmetics for its moisturizing and reparative effects on the skin[6], but it is also under clinical development as a botanical drug for cognitive decline[1]. It has shown low potential for cytochrome P450-mediated drug interactions in vitro[1].

Other names

centella asiatica aqueous extractgotu kola water extractcica water extractwater navelwort extract