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Centi-B9 is an investigational broad-spectrum anti-coronavirus **monoclonal antibody** developed by Centivax for the treatment and prevention of COVID-19 caused by SARS-CoV-2. It is described as a broadly neutralizing antibody directed against the **SARS-CoV-2 spike protein**, with reported activity against multiple viral variants and a formulation engineered for high stability and low viscosity at high concentration, enabling **intramuscular injection** rather than conventional intravenous infusion. The program has been positioned for both therapeutic and prophylactic use, with claimed single-dose protection lasting approximately 28 to 42 days, and was reported to be advancing toward Phase 1 development in collaboration with the U.S. Naval Medical Research Center.
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