Central South Univ. HIPK2 compound 15q

Central South Univ. HIPK2 compound 15q: sourced facts only. name: "Compound 15q displayed good selectivity and potent inhibitory activity against HIPK2 compared to other two subtype enzymes." [PMID:35636124]; target: "Compound 15q displayed good selectivity and potent inhibitory activity against HIPK2 compared to other two subtype enzymes." [PMID:35636124]; developer: "Department of Medicinal Chemistry, Xiangya School of Pharmaceutical Sciences, Central South University, Changsha 410013, Hunan, China; Hunan Key Laboratory of Diagnostic and Therapeutic Drug Research for Chronic Diseases, Changsha 410013, Hunan, China; Hunan Key Laboratory of Organ Fibrosis, Changsha 410013, Hunan, China." [PMID:35636124]; stage: "Notably, 15q displayed encouraging in vivo anti-fibrotic effects in the unilateral ureteral obstruction mouse model, which could be used as a potential lead for structural optimization and candidate for the development of selective HIPK2 inhibitors." [PMID:35636124]