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Centrum
- Development stage
- Unknown
- Lead developer
- HALEON
- Administration
- Oral
01
Overview
Centrum is a widely recognized brand of multivitamin and multimineral dietary supplements. In the context of clinical oncology, specifically in trials for non-small cell lung cancer (NSCLC) involving the chemotherapy agent pemetrexed (such as those conducted by Jiangsu Simcere Pharmaceutical), Centrum is administered as a mandatory supportive care intervention. Its primary role in this setting is to provide folic acid supplementation, which is required to mitigate the hematologic and gastrointestinal toxicities associated with pemetrexed by ensuring adequate folate stores for cellular metabolism and DNA synthesis.
- Brand names
- Centrum
- Other names
- MultivitaminMultimineral
02
Targets
VDR (Vitamin D receptor)
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