Drug intelligence / Profile preview

Centrum Turmeric Extract

Development stage
Unknown
Lead developer
Especialidades Farmacéuticas Centrum
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Centrum Turmeric Extract (also known as Extracto de cúrcuma Centrum) is a standardized botanical extract of Curcuma longa (turmeric) rhizome containing 12% curcumin. Developed and manufactured by Especialidades Farmacéuticas Centrum (a subsidiary of Asacpharma), it is approved in Spain as an oral traditional herbal medicine for the treatment of hepatobiliary functional digestive disorders, such as heavy digestion and flatulence, by acting as a choleretic and cholagogue to facilitate bile production and flow. Additionally, the extract has been investigated in Phase IV clinical trials for the treatment of moderate-to-severe plaque psoriasis in combination with visible light phototherapy, leveraging its anti-inflammatory and antioxidant properties.

Brand names
Extracto de cúrcuma Centrum
Other names
Centrum Turmeric Extract 12% curcuminCentrum turmeric extract standardised to 12% curcumincurcuma extractcurcuma longa rhizome extract
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX5 (Arachidonate 5-lipoxygenase)

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