cephaloridine

Cephaloridine is a semisynthetic, broad-spectrum first-generation cephalosporin antibiotic derived from cephalosporin C. It acts by binding to and inactivating penicillin-binding proteins (PBPs) on the inner membrane of bacterial cell walls. This inhibits the final stages of peptidoglycan cross-linking necessary for cell wall strength and rigidity in bacteria, leading to cell lysis and death. Cephaloridine was introduced in the early 1960s and was used primarily for treating urinary tract infections as well as lower respiratory tract infections before being withdrawn from human use due to nephrotoxicity concerns. It is now mainly used in veterinary medicine[1][2][3][4][5][8].

Brand names

ceporin

Other names

cephaloridinecefaloridinecefalorizincephalomycine