cephalosporin C

Cephalosporin C is a naturally occurring beta-lactam antibiotic of the cephalosporin class, originally isolated from the fungus Acremonium chrysogenum. It was first characterized in 1961 and served as the lead compound for the development of many synthetic cephalosporins, such as cefalotin. Cephalosporin C itself has weak antibacterial activity and was never commercialized as a therapeutic drug. Its mechanism of action involves inhibition of penicillin binding proteins (PBPs), which are enzymes essential for bacterial cell wall synthesis, leading to bactericidal effects. Cephalosporins are generally used to treat various bacterial infections, especially in patients allergic to penicillins[6][9][1].

Other names

7-(5-amino-5-carboxyvaleramido)cephalosporanic acidCHEBI:157763XIY7HJT5L