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CER-081 is a preclinical-stage small molecule ketone precursor being developed by Cerecin (formerly Accera) for the treatment of acute neurological conditions, including traumatic brain injury (TBI) and stroke. Administered parenterally, CER-081 is designed to rapidly provide ketone bodies as an alternative metabolic substrate to the brain during periods of metabolic crisis or glucose hypometabolism following acute injury. This neurometabolic approach aims to support brain energy metabolism and mitigate secondary injury in settings where rapid metabolic support is required, offering a potential therapeutic option for patients in emergency neurological care.
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