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CeraVe Itch Relief Moisturizing Lotion
- Development stage
- Unknown
- Lead developer
- L'Oréal
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
CeraVe Itch Relief Moisturizing Lotion is an over-the-counter topical anesthetic and moisturizer developed by L'Oréal's CeraVe brand. Its primary active ingredient is 1% pramoxine hydrochloride, a small molecule topical anesthetic that provides rapid relief from itching (within 2 minutes) for up to 8 hours. The formulation is specifically designed for temporary relief of pruritus associated with minor skin irritations, insect bites, sunburn, poison ivy, and dry skin. In addition to its anesthetic properties, the lotion contains a blend of three essential ceramides (1, 3, and 6-II), hyaluronic acid, and niacinamide, which work synergistically to restore the skin's natural protective barrier and maintain hydration. It is steroid-free, fragrance-free, and non-comedogenic, making it suitable for sensitive and eczema-prone skin.
- Brand names
- CeraVe Itch Relief Moisturizing Lotion
- Other names
- IRML
02
Targets
NaV (Voltage-gated sodium channels)
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