Drug intelligence / Profile preview

Cerebiome

Development stage
Phase 4
Lead developer
Lallemand Health Solutions
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Cerebiome is a proprietary psychobiotic formulation developed by Lallemand Health Solutions, consisting of two specific probiotic strains: *Lactobacillus helveticus* Rosell-52 and *Bifidobacterium longum* Rosell-175. It is specifically designed to target the gut-brain axis to support mental health, particularly in the management of stress, anxiety, and depression. The product works by modulating the hypothalamic-pituitary-adrenal (HPA) axis to reduce cortisol levels, decreasing systemic pro-inflammatory cytokines (such as TNF-alpha and IL-6), and promoting the production of neuroprotective factors. It is one of the most extensively researched probiotic combinations for mood disorders, with clinical evidence supporting its use as both a standalone supplement and an adjunct to conventional antidepressant therapy.

Brand names
CerebiomeProbio'StickProbioStick
Other names
Lactobacillus helveticus Rosell-52 + Bifidobacterium longum Rosell-175L. helveticus R0052 + B. longum R0175

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