cetirizine + chlorpheniramine + methylprednisolone

This combination therapeutic regimen was utilized as the conventional treatment arm in a Phase 2 clinical trial conducted by the National Polytechnic Institute (IPN) in Mexico for pediatric patients with moderate atopic dermatitis. The regimen consists of two systemic antihistamines—cetirizine (a second-generation H1 antagonist) and chlorpheniramine (a first-generation H1 antagonist)—alongside a topical corticosteroid, methylprednisolone aceponate 0.1%. This combination aims to manage the pruritus and inflammatory skin lesions associated with atopic dermatitis. In the specific trial context, it served as the standard-of-care comparator against which the efficacy of Transferon (Dialyzed Leukocyte Extracts) was measured as an adjuvant therapy.

Other names

conventional treatment-National Polytechnic Institute, Mexico-atopic dermatitisconventional treatment (National Polytechnic Institute, Mexico)standard treatment for atopic dermatitis (IPN study)