Drug intelligence / Profile preview

Cetolán

Development stage
Unknown
Lead developer
Laboratorios Columbia
Modality
Small Molecules
Administration
Topical
01

Overview

Cetolán is a topical over-the-counter (OTC) analgesic gel developed and marketed by Laboratorios Columbia. Its primary active ingredient is ketorolac tromethamine, a nonsteroidal anti-inflammatory drug (NSAID) that provides local relief from pain and inflammation. The drug functions by inhibiting the cyclooxygenase enzymes (COX-1 and COX-2), which are responsible for the synthesis of prostaglandins that mediate the inflammatory response and pain signaling. Cetolán is specifically indicated for the local treatment of mild to moderate musculoskeletal pain, including conditions such as sprains, strains, and minor sports injuries. It is formulated as a 2% gel for direct application to the affected area, allowing for localized therapeutic effects with minimal systemic absorption compared to oral NSAIDs.

Brand names
Cetolán
Other names
ketorolac tromethamine topical
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)PGHS-1 (Prostaglandin G/H Synthase 1)

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