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CG-102-12 is an investigational drug candidate that acts as a glypican 3 (GPC3) inhibitor. It was initially developed by Sethkin Biotechnology (Shanghai) and is being studied for the treatment of hepatocellular carcinoma, a primary form of liver cancer. GPC3 is a cell surface heparan sulfate proteoglycan highly expressed in hepatocellular carcinoma and implicated in tumor growth and progression, making it an attractive therapeutic target. The precise modality or molecular format of CG-102-12 has not been disclosed in public sources, but its mechanism involves inhibition or modulation of GPC3 function to exert antitumor effects[1][2].
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