Drug intelligence / Profile preview

CG210

Development stage
Unknown
Lead developer
Legacy Healthcare
Modality
Drug Delivery Systems
Administration
Topical
01

Overview

**CG210** is a patented topical botanical lotion developed for treating androgenetic alopecia (AGA) in both men and women, featuring a unique blend of onion bulb extract (Allium cepa), lemon fruit extract (Citrus medica Limonum), cocoa seed extract (Theobroma cacao), and guarana seed extract (Paullinia cupana). It operates via a triple mechanism of action distinct from existing therapies: it increases Bcl-2 anti-apoptotic protein levels (up to 89.9%) to prolong the anagen phase and prevent premature follicle cell apoptosis, attenuates scalp micro-inflammation by enhancing Langerhans cells (73.9% increase in CD1A+ cells) and cellular proliferation (41.7% increase in Ki-67+), and boosts scalp collagen by 79.9% after 4 months to support healthier hair implantation. Clinical trials demonstrate reduced hair shedding to normal levels within 44 days, 11% increase in anagen hairs after 3 months, and 37.7% greater hair diameter increase versus placebo when combined with finasteride over 12 months, with high patient satisfaction (96% clinical improvement), excellent safety (no side effects reported), and hypoallergenic, non-oily formulation eligible for EMA centralized herbal medicine registration.[1][2][3][5][7][8][9]

Brand names
CG210CG-210CG 210
02

Targets

BCL-2 (BCL-2 family)

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