Drug intelligence / Profile preview

Chai Ge Antipyretic Oral Solution

Development stage
Phase 2
Lead developer
Shanghai Yuzhihua Pharmaceutical Technology
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Chai Ge Antipyretic Oral Solution is a Traditional Chinese Medicine (TCM) formulation developed by Shanghai Yuzhihua Pharmaceutical Technology for the treatment of acute upper respiratory tract infections (URTI). It is specifically indicated for patients presenting with the "wind-heat" pattern, a TCM diagnostic category characterized by symptoms such as fever, sore throat, and headache. The formulation is derived from classical herbal prescriptions, likely featuring *Bupleurum chinense* (Chai Hu) and *Pueraria lobata* (Ge Gen) as primary active components, which are traditionally recognized for their antipyretic, analgesic, and anti-inflammatory properties. The drug has undergone Phase 2 clinical evaluation in China to assess its efficacy and safety in reducing fever and alleviating related clinical symptoms in adult patients compared to placebo.

Other names
Chai Ge Jie Re Kou Fu Ye柴葛解热口服液

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